HincII and Kpnl RFLPs for laminin B1 (LAMB1) gene on chromosome 7
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چکیده
منابع مشابه
Two RFLPs in human inter-alpha-trypsin inhibitor heavy chain gene ITIH2 on chromosome 10.
SOURCE AND DESCRIPTION OF CLONE : The 0.8 kb Eco RI / Bam HI fragment of lambda HuHITI-9 (1) used as a probe codes for human heavy chain H2 of the inter-alpha-trypsin inhibitor (2). POLYMORPHISMS : Kpn 1 (GGTAC/C) identifies one invariant band at 8.5 kb and a diaJlelic polymorphism with DNA fragments at 26.0 kb or 20.0 kb. Msp I (C/CGG) identifies three invariant bands at 2.35 kb, 2.1 kb and 1....
متن کاملras gene mutations and clonal analysis using RFLPs of X-chromosome genes in myelodysplastic syndromes.
Myelodysplastic syndromes (MDS) comprise a heterogeneous group of clonal disorders characterized by quantitative and qualitative abnormalities of hematopoiesis [1, 2]. Up to 30% of cases eventually develop into acute nonlymphocytic leukemia (ANLL). Previous observations by us and others have demonstrated a frequent (30%) activation of the N-ras oncogene in ANLL [3-6]. The involvement of the dif...
متن کاملHuman PEG1/MEST, an imprinted gene on chromosome 7.
The mouse Peg1/Mest gene is an imprinted gene that is expressed particularly in mesodermal tissues in early embryonic stages. It was the most abundant imprinted gene among eight paternally expressed genes (Peg 1-8) isolated by a subtraction-hybridization method from a mouse embryonal cDNA library. It has been mapped to proximal mouse chromosome 6, maternal duplication of which causes early embr...
متن کاملTwo 47z [DXYS5] RFLPs on the X and the Y chromosome.
Source and Description 47z (DXYS5), located on the short arm of Ychromosome, i s a 2.3Kb EcoRI/Mbol fragment inserted in to the EcoRI s i t e of pBR322 with a BamHI/EcoRI l inker (1 ) . Homologous sequence i s located on Xq21. Polymorphism 1. Y-chromosome polymorphism: StuI iden t i f i e s a two-al lele polymorphism at 17Kb and 5.3Kb. 2. X-chromosome polymorphism: Hindlll-TaqI double digestion...
متن کاملRole of the B1 short arm in laminin self-assembly.
Laminin self-assembles into a basement membrane polymer through specific low-affinity interactions. Recently, it was shown that the terminal short-arm domain (domains VI and V) of the B1 chain (fragment E4) possesses one of the laminin self-interaction sites [Schittny, J.C. & Yurchenco, P.D. (1990) J. Cell Biol. 110, 825-832], but that the binding partner(s) of this domain is unknown. Using aff...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1988
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/16.17.8742